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Image de profil de Aurélia  Sima
Membre de l'Acfas

Aurélia Sima

« Our research explores metabolism renegotiation in obesity, insulin resistance, diabetes and their cardiovascular  and renal complications. We have shown that adipose tissues topography influences retinoid metabolism (Sima A et al.2011). Our retinoid treatment on ob/ob mice decreases body fat, visceral adiposity, serum RBP4, ROL and insulin resistance and induces beige/brown fat, also restoring cardio-protective OT-NP system and preventing cardiac apoptosis and fibrosis (Manolescu et al 2010,2014). To our knowledge, so far, we are the only Canadian team investigating obesity, insulin resistance, diabetes and their cardiovascular  and renal complications, with a retinoid approach in both, fundamental and applied research »: " Lipid metabolism in mammalian tissues and its control  by retinoic acid " Bonet, M.L.,Ribot J., Palou A.,Biochim Biophys Acta 2011 / 1821 (1):177-89; Dr. Daniel Constantin Manolescu, PhD (MR), MSc (MR), BSc (Ing), CBA;  Dr. Aurelia Sima, PhD (MR), MSc (MR), BSc (Ing), CBA

Principal secteur de recherche ou d'activité

Sciences de la santé

Mes intérêts de recherche

Diététique et nutrition Endocrinologie Physiologie Biologie moléculaire Cardiologie

Mes contributions « Science et société »

  • https://www.google.com/search?client=firefox-b-d&q=aurelia+sima

Mes publications

https://www.researchgate.net/publication/274095499_Retinoid_and_Related_Molecules_as_Biomarkers_in_Obesity_and_Insulin_Resistance

https://www.researchgate.net/publication/273428699_P2139_Les_Retinoides_Dans_L'evaluation_Precoce_Du_Syndrome_Metabolique_Et_Diabete_De_Type_2_Humain

https://www.researchgate.net/publication/273623055_P1054_L'influence_de_la_vitamine_a_ROL_RA_sur_le_metabolisme_energetique_et_l'homeostasie_du_glucose_chez_des_souris_diabetiques_ObOb

https://www.nrcresearchpress.com/doi/10.1139/o11-062#.XlqTPPZFwdU

http://www.nutristep.ca/en/pdfs/2017_-_CanadianNutritionSocietyScientificAbstractsfromthe[retrieved_2017-08-23].pdf

https://www.ncbi.nlm.nih.gov/pubmed/22077479

https://www.ncbi.nlm.nih.gov/pubmed/20032483

https://www.sciencedirect.com/science/article/pii/S0304416509002669

https://www.researchgate.net/publication/40767972_All-trans_Retinoic_Acid_Lowers_Serum_Retinol-Binding_Protein_4_Concentrations_and_Increases_Insulin_Sensitivity_in_Diabetic_Mice

http://publications.gc.ca/site/archivee-archived.html?url=http://publications.gc.ca/collections/collection_2014/irsc-cihr/MR12-8-13-9-fra.pdf

https://app.dimensions.ai/details/publication/pub.1006933650 

https://www.ncbi.nlm.nih.gov/pubmed/19766701

https://www.ncbi.nlm.nih.gov/pubmed/?term=Aurelia+Sima

 

Mes prix et distinctions

  • 2012
    CRCHUM- Bourse Excellence Doctorat, Axe Cardio-métabolique, 6-éme / 33 PhD. Cdt.
  • 2013
    CIHR/IRSC - Bourse Rayonnement Doctorat, Institut de la Nutrition, du Métabolisme et du Diabète, 4-éme / 12 PhD./Cdt.
  • 2012
    FESP UdeM - Bourse Excellence PhD « J.A. de Sève » / sponsored by Toronto Dominion Bank , Canada
  • 2014
    Diabète Québec - Bourse Excellence PhD, Cardio-Métabolique - nouveaux marqueurs prédiabétiques
  • 2015
    CRCHUM- Bourse Excellence Doctorat, Axe Cardio-métabolique, 3-éme / 10 PhD. Cdt.

Mes affiliations

  • Dr. Aurelia Sima, PhD, MSc, BSc.(ing.) Nutrition and Metabolism; Food Chemistry
  • CIHR - Canadian Institutes of Health Research, DQ - Diabète Québec, CIFST- Canadian Institut of Food Science and Technology, CNS - Canadian Nutrition Society, DC - Dietitians of Canada, SQLNM-Société Québécoise de Lipidologie, de Nutrition et de Métabolisme, ACFAS - Association Francophone pour le Savoir, ISNN-International Society of Nutrigenomic/Nutrigenetics