Ronald St-Louis
I am a young research fellow who is pursuing a career as an independent investigator. I devote 100 % of my time in research. I have developed my scientific autonomy, both in the context of assimilating scientific literature, and in the development of experimental protocols, capable now of conducting a research project by myself. I am still pursuing my journey and my specialization in the field of vascular biology specifically in diabetes. Coming from a background in microbiology and neuroendocrinology, throughout my research experience, I have gained solid training in the areas of in vivo animal work, reactive oxygen species (ROS) and vascular biology. I have become versatile in particular techniques of animal surgery, physiology, molecular and cell biology, biochemistry and microbiology. During my PhD thesis in Paris France, and my first postdoctoral fellow in Quebec Canada, I contributed to develop different techniques, some entirely new to the laboratory. I also worked as a postdoctoral research fellow at the Joslin Diabetes Center, seeking to learn new scientific knowledge. Among my main interests was to increase my understanding of the brain function in the context of homeostasis, the vascular rigidity in case of chronic kidney disease, and the pathophysiology of diabetes in case of diabetic nephropathy.
Principal secteur de recherche ou d'activité
Mes publications
1- Gordin D, Shah H, Shinjo T, St-Louis R, Qi W, Park M, Paniagua S, Pober DM, Wu IH, Bahnam V, Brissett MJ, Tinsley LJ, Dreyfuss JM, Pan H, Dong Y, Niewczas MA, Amenta P, Sadowski T, Kannt A, Keenan HA, King GL (2019) Characterization of glycolytic enzymes and pyruvate kinase M2 in type 1 and 2 diabetic nephropathy. Diabetes Care. 42(7):1263-1273
2- Park K, Li Q, Evcimen ND, Rask-Madsen C, Maeda Y, Maddaloni E, Yokomizo H, Shinjo T, St-Louis R, Fu J, Gordin D, Khamaisi M, Pober D, Keenan HA, King GL (2018) Exogenous Insulin Infusion Can Decrease Atherosclerosis in Diabetic Rodents by Improving Lipids, Inflammation, and Endothelial Function. Arterioscler Thromb Vasc Biol. 38(1):92-101
3- Maddaloni E, Xia Y, Park K, D’Eon S, Tinsley LJ, St-Louis R, Khamaisi M, Li Q, King GL and Keenan HA (2017) High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes. Cardiovasc Diabetol. 16(1):116
4- Agharazii M, St-Louis R, Gautier-Bastien A, Ung RV, Mokas S, Larivière R, Richard DE. (2015) Inflammatory cytokines and reactive oxygen species as mediators of chronic kidney disease related-vascular calcification. American Journal of Hypertension. 28(6):746–755
5- St-Louis R, Parmentier C, Grange-Messent V, Mhaouty-Kodja S, Hardin-Pouzet H. (2014) Reactive oxygen species are physiological mediators of the noradrenergic signalling pathway in the mouse supraoptic nucleus. Free Radical Biology and Medecine. 71 : 231-239
6- St-Louis R, Parmentier C, Raison D, Grange-Messent V, Hardin-Pouzet H. (2012) Reactive oxygen species are required for the hypothalamic osmoregulatory response. Endocrinology. 153(3): 1317-1329
7- Vacher CM, Grange-Messent V, St-Louis R, Raison D, Lacorte JM, Hardin-Pouzet H. (2011) Architecture of the hypothalamo-posthypophyseal complex is controlled by monoamines. Journal of Neuroscience Research. 89(11): 1711-1722
Mes affiliations
- Evotec International GmbH; Joslin Diabetes Center; Harvard Medical School